Name: RNA World
Uploaded: 2019-07-19
Duration: 5 min 49 s
Description: We know our DNA stores information, and the RNA reads it and transmits it. But which one appeared first? Let’s find out how this really works.

Question

Describe post transcriptional processing of RNA in eukaryotes.

Accepted Answer

During post-transcriptional modification in eukaryotes, primary transcript RNA is converted into a mature mRNA. It occurs before the translation process inside the nucleus. The processing of RNA in eukaryotes involves three steps, namely capping, poly-adenylation, and splicing.

Capping: There is the addition of 7-methylguanosine to the 5' end of RNA. Ribosome recognizes mRNA with the 5' cap during the translation process.

Poly-adenylation: It involves the addition of poly-A tail (multiple A residue) to the 3' end of RNA. About 259 adenine residues are added to the 3' end of the RNA.

Splicing: A process in which introns (non-coding regions) are removed from the pre-RNA and exons (coding regions) are joined together to form a mature RNA. The modified RNA strand, that is, mRNA moves to the cytoplasm and to be encoded for the polypeptide formation.

Describe post transcriptional processing of RNA in eukaryotes.

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