MEDIUM
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Huntington's disease is a sex-linked disease.

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Important Questions on Inheritance

HARD
Pick out the correct statements:
(i) Haemophilia is a sex-linked recessive disease.
(ii) Down's syndrome is due to aneuploidy.
(iii) Phenylketonuria is an autosomal recessive gene disorder.
(iv) Sickle cell anaemia is an X-linked recessive gene disorder.
EASY
State two reasons why the blood of haemophilia persons clot very slowly or not at all.
HARD
Generally, it is observed that human males suffer from haemophilia more than human females, who rarely suffer from it. Explain giving reasons. 
HARD
When a normal female is married to a colour-blind male, then work out the colour blindness in the progeny of these parents with the help of a diagram.
EASY
A couple has two sons and two daughters. Only one son is colour blind and the rest of the siblings are normal. Assuming colour blindness is sex-linked, which ONE of the following would be the phenotype of the parents?
MEDIUM
Why is haemophilia uncommon in females?
EASY
A woman (whose father is haemophilic and mother is homozygous normal) married a normal man and had two sons and two daughters. What are the chances of their sons being haemophilic?
HARD
Satish is a colour blind boy. His mother has normal vision but his maternal grandfather is colour blind. His father and maternal grandmother have normal vision. Explain the pattern of inheritance with a suitable chart.
EASY
Which of the following muscular disorders is inherited?
MEDIUM
A man whose father was colour blind marries a woman who had a colour blind mother and normal father. What percentage of male children of this couple will be colour blind?
HARD
Match the human disorders shown in Group I with the biochemical processes in Group II. Choose the correct combination.
 
Group I Group II
P. Phenylketonuria i. Melanin synthesis
Q. Albinism ii. Conversion of Phenylalanine to Tyrosine
R. Homocystinuria iii. Tyrosine degradation
S. Argininemia iv. Methionine metabolism
  v. Urea Synthesis
HARD
A colourblind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their sons being colourblind?
HARD
Write the main characteristic features of colour blindness. What will be the hereditary of the offspring when a colourblind man marries with a normal female? Explain it with ray diagram.
HARD
If the mother is a carrier of colour blindness and the father is normal, show the possible genotype and phenotype of the offspring of the next generation with the help of a punnet square.
EASY
What is sex-linked inheritance? Give one example.
MEDIUM
A carrier haemophilic female marries a normal male. What will be the phenotype of progeny? Explain with suitable chart.
EASY
"The gene for sickle cell anaemia in homozygous condition is lethal and produces sickle cell trait in heterozygous carrier*. Explain.
MEDIUM
Both male and female have normal vision though their fathers were colour-blind, and mothers did not have any gene for colour blindness. The probability of their daughter becoming colour-blind is
MEDIUM

A woman heterozygous for colour blindness marries a colour-blind man. What would be the ratios of carrier daughters, colour-blind daughters, normal sons, and colour-blind sons in the F1 generation?

MEDIUM
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is