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If a gene follows a criss-cross pattern of inheritance, it is a

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Important Questions on Inheritance and Variation

MEDIUM
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is
HARD
Pick out the correct statements:
(i) Haemophilia is a sex-linked recessive disease.
(ii) Down's syndrome is due to aneuploidy.
(iii) Phenylketonuria is an autosomal recessive gene disorder.
(iv) Sickle cell anaemia is an X-linked recessive gene disorder.
HARD
In the following human pedigree, the filled symbols represents the affected individuals. Identify the type of given pedigree.


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EASY
Which of the following muscular disorders is inherited?
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Satish is a colour blind boy. His mother has normal vision but his maternal grandfather is colour blind. His father and maternal grandmother have normal vision. Explain the pattern of inheritance with a suitable chart.
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Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement.
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A colourblind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their sons being colourblind?
EASY
A change of single base pair in the gene for beta globin chain (in human haemoglobin) that results in the change of amino acid residue glutamine to valine which is due to
MEDIUM
A carrier haemophilic female marries a normal male. What will be the phenotype of progeny? Explain with suitable chart.
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A woman has X-linked condition on one of her X chromosomes. These chromosomes can be inherited by:
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Statement I : All the three types of allosomal genes - X linked, Y linked and XY linked are present only in male human being.
Statement II : Only X linked and not XY linked genes are present in female human being.

The correct option among the following is

EASY
Point mutation is caused in which of the following diseases?
EASY
A couple has two sons and two daughters. Only one son is colour blind and the rest of the siblings are normal. Assuming colour blindness is sex-linked, which ONE of the following would be the phenotype of the parents?
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In an Organism, mutation in a single gene exhibits multiple phenotypic expression. Identify the underlying genetic mechanism in the above instance.
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Which one of the following conditions is not responsible for the presence of deoxygenated blood in the arteries of a newborn?
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Statement (S): The heterozygous individuals for sickle-cell anaemia HbAHbS express disease phenotype and also carriers of the disease.

Reason (R): HbAHbS genotype individuals are resistant to severe effects of malaria.

The correct answer is

EASY
Which of the following most appropriately describes haemophilia?
EASY
Which ONE of the following Mendelian diseases is an example of X-linked recessive disorder?
MEDIUM
A man whose father was colour blind marries a woman who had a colour blind mother and normal father. What percentage of male children of this couple will be colour blind?