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In a DNA molecule, if the number of phosphodiester bonds is 198, it has ______ bases.

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Important Questions on Molecular Basis of inheritance

HARD
Describe Watson and Crick Model of DNA with diagram.
EASY
Assertion (A): Purine always comes opposite to a pyrimidine.
Reason (R): Appropriate uniform distance is maintained between the two strands of the DNA helix.
MEDIUM
Write the dual purpose served by deoxyribonucleoside triphosphate in polymerisation.
EASY
Considering the average molecular mass of a base to be 500 Da, what is the molecular mass of double stranded DNA of 10 base pairs?
HARD
The average energy of each hydrogen bond in A-T pair is x kcalmol-1 and that in G-C pair is y kcalmol-1. Assuming that no other interaction exists between the nucleotides, the approximate energy required in kcalmol-1 to split the following double stranded DNA into two single strands is
Question Image
[Each dashed line may represent more than one hydrogen bond between the base pairs]
EASY
What is a palindrome? Give an example of a palindromic sequence.
MEDIUM
Sugar moiety in DNA and RNA molecules respectively are
HARD
A newly discovered organism possesses a genetic material with a new base composition consisting of the sugar and phosphate backbone as found in existing natural DNA. The five novel bases in this genetic material-namely, P,Q,R,S,T are heterocyclic structures with 1,1,2,2 and 3 rings, respectively. Assuming the new DNA forms a double helix of uniform width, which one of the following would be the most appropriate base pairing?
MEDIUM

Match the following lists:

  List I   List II
A) X-ray diffraction data I) Chargaff
B) DNA double stranded II) Meischer
C) DNA double helix III) Wilkins
D) DNA as an acidic substance IV) Watson & Crick

The correct match is

MEDIUM
What is the length of human DNA containing 6.6×109 bp ?
HARD

Assertion (A): Between DNA and RNA, DNA is a better genetic material.

Reason (R): 2' -OH group present in every nucleotide in RNA is a reactive group and make RNA labile and easily degradable.

The correct answer is:

HARD
Describe with labelled diagram of Watson and Crick model of DNA.
MEDIUM
With the help of a suitable example illustrate ‘Palindrome’.
EASY
If one strand of a DNA has the sequence of bases TATCTACCTGGA. Write the sequence of bases on the complementary strand.
EASY
Which of the following is a palindromic sequence of base pairs?
HARD
A bacteriophage T2 particle contains within its head a double-stranded B-from DNA of molecular weight 1.2×108 Da. Assume that the head of a T2 Phage particle is of 210nm in length and the average molecular weight of a nucleotide is 330 Da. The length of the T2 genome is in the range of
MEDIUM
DNA molecule which has the highest number of hydrogen bonds