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In humans, attached earlobes are a dominant feature over free earlobes while hypertrichosis of the ear is a holandric (Y-linked) feature. A man with attached earlobes and extensive hair on pinna married a woman having free earlobes. The couple had one son with attached earlobes and hairy pinna, another son with free earlobes and hairy pinna and two daughters with attached earlobes. One of the daughters married a man with free earlobes and sparse hair on pinna. They had two sons. What would be the characteristics of their pinnae?

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Important Questions on Principles of Inheritance and Variation

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Due to nondisjunction of chromosomes during spermatogenesis, some sperms carry both sex chromosomes (22A+XY) and some sperms do not carry any sex chromosome (22A+O). If these sperms fertilise normal eggs (22A+X), What types of genetic disorders respectively appear among the offspring?
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Refer to the given statements.

(i) Incomplete or mosaic inheritance is an example of the pre-Mendelian concept of blending inheritance.

(ii) Test cross is a special type of back cross.

(iii) Chromosomal aberrations are commonly observed in cancer cells.

(iv) Thalassaemia is a Mendelian disorder.

Which of the above statements are correct?

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If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?
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Study the given pedigree chart for sickle-cell anaemia and select the most appropriate option for the genotypes.

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The disease sickle-cell anaemia is caused by the substitution of (i)... by (ii).... at the (iii).... position of (iv).... globin chain of the haemoglobin molecule. Which of the following correctly fills the blanks in the above statement?
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A colourblind man XCY marries a woman who is carrier for haemophilia (XXh). Which of the following is true for their progenies?
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Read the following statements and state true (T) and false (F):

A. Mendel experimented on 14 true breeding pea plant varieties.

B. Mendel conducted hybridization experiments on garden pea from 1856 to 1863.

C. All genes for seven characters studied by Mendel were located on same chromosomes.

D. Mendel’s work on inheritance of characters remain unrecognized for 16 years after his death.