MEDIUM
Upper Secondary-IGCSE
IMPORTANT
Earn 100

The family tree (pedigree) in figure 16.3 shows the incidence of a genetic disease called phenylketonuria (PKU) in four generations of a family.

Question Image

If PKU is caused by a recessive allele, explain why it is unlikely that this allele first appeared in person 4.

Important Questions on Inheritance

MEDIUM
Upper Secondary-IGCSE
IMPORTANT

The family tree (pedigree) in figure 16.3 shows the incidence of a genetic disease called phenylketonuria (PKU) in four generations of a family.

Question Image

In the space below, deduce the possible genotypes of person 1, 2, 3 and 4. Use the symbol q for the PKU allele and the symbol Q for the normal allele.

MEDIUM
Upper Secondary-IGCSE
IMPORTANT

The family tree (pedigree) in figure 16.3 shows the incidence of a genetic disease called phenylketonuria (PKU) in four generations of a family.

Question Image

Person 5 is worried that her children might have PKU. She talks to a genetic counsellor. What might she be told?

MEDIUM
Upper Secondary-IGCSE
IMPORTANT

In fruit flies, as humans, males have an X and a Y chromosome, and females have two X chromosomes.

There is a gene on the X chromosome that affects eye colour. The dominant allele of this gene produces red eyes, and the recessive allele produces white eyes.

Suggest suitable symbols for the two alleles of this gene.

HARD
Upper Secondary-IGCSE
IMPORTANT
In the space below, construct a genetic diagram to predict the ratios of eye colour in male and female offspring of a white-eyed male fly and a heterozygous red-eyed female fly.
EASY
Upper Secondary-IGCSE
IMPORTANT
Name two types of protein whose function depends on the precise shape of the molecule.
MEDIUM
Upper Secondary-IGCSE
IMPORTANT
Explain why a change in the structure of a DNA molecule could result in the loss of function of proteins.
MEDIUM
Upper Secondary-IGCSE
IMPORTANT
State how the genes contained in the specialised cells differ, if at all, from the genes contained in the stem cells.
MEDIUM
Upper Secondary-IGCSE
IMPORTANT
Explain what happens to the genes in a cell, as it becomes specialised for their specific function.