EASY
Earn 100

What is transition and transversion?

Important Questions on Principles of Inheritance and Variation

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Explain the type of gene mutation in the DNA sequence given below.

ATGCATGC  ATGAATGC

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Virulent forms of the bacterium staphylococcus aureus is a human pathogen, some strains of which cause “flesh-eating disease”. Earlier the antibiotic Penicillin was used to control this pathogen. After some years Penicillin was ineffective. Hence, a powerful antibiotic-Methicillin was used in treatments. Subsequently, Methicillin also became ineffective and the strains showed resistance to multiple antibiotics also called “multi-drug resistance”. Which one of the following statements regarding the development of multi-drug resistance is correct?
MEDIUM
Select the incorrect statement on Mutations ? 
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The mechanism that causes a gene to move from one linkage group to another is called:
EASY

Give one significant difference between the following:

Transition and transversion

HARD
A spontaneous mutation results in a couple having only female progeny. When the daughter marries and has children, none of them are males. However, in the third generation, there are few male offspring. What is the most likely explanation of this observation?
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The mutation of a purine to a pyrimidine is known as
MEDIUM
The movement of a gene from one linkage group to another is called:
HARD

Match the following lists:

  List I   List II
A) Change in single base pair of DNA I) Recombination
B) Deletions of base pairs of DNA II) Genetic map
C) Generation of non-parental gene combination III) Point mutations
D) The frequency of recombination between gene pairs on the same chromosome IV) Frame-shift mutations

The correct match is

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When one or more genes are missing from middle part of chromosome, it is called
MEDIUM
The idea of mutations was brought forth by:
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Chromosomal aberrations are commonly observed in_____.

MEDIUM
In which of the following chromosomal aberrations, is there a change in gene number?
EASY
To be evolutionarily successful, a mutation must be:
HARD

Read the following statements and state true (T) and false (F):

A. Deletions and insertions of base pairs of DNA cause frame shift mutations.

B. Classical example of point mutation is sickle cell anaemia.

C. Mendelian disorders are mainly determined by alteration or mutation in a single gene.

D. Haemophilia, colour blindness, and cystic fibrosis are sex-linked recessive disorders.

MEDIUM

Read the following statements:

A. The phenomenon which results in alteration of DNA sequence and consequently results in changes in genotype and the phenotype of an organism.

B. In addition to recombination, it is another phenomenon that leads to variation in DNA.

The phenomenon explained above is

EASY
Using imprints from a plate with complete medium and carrying bacterial colonies, you can select streptomycin resistant mutants and prove that such mutations do not originate as adaptation. These imprints need to be used