Which of the following conditions is caused by mutations that involves the entire chromosome rather than a gene?
Important Questions on Principles of Inheritance and Variation
Which of the following statements are correct about Klinefelter's Syndrome?
A. This disorder was first described by Langdon Down (1866).
B. Such an individual has overall masculine development. However, the feminine development is also expressed.
C. The affected individual is short statured.
D. Physical, psychomotor and mental development is retarded.
E. Such individuals are sterile.
Choose the correct answer from the options given below:
(i) Haemophilia is a sex-linked recessive disease.
(ii) Down's syndrome is due to aneuploidy.
(iii) Phenylketonuria is an autosomal recessive gene disorder.
(iv) Sickle cell anaemia is an X-linked recessive gene disorder.
Match the Column- I with Column - II
| Column - I | Column - II | ||
| i | Autosomal trisomy | p | Turner's Syndrome |
| ii | Allosomal trisomy | q | Mendelian disorder |
| iii | Allosomal Monosomy | r | Klinefelter's Syndrome |
| iv | Cystic fibrosis | s | Down's Syndrome |
| Group I | Group II |
| P. Phenylketonuria | i. Melanin synthesis |
| Q. Albinism | ii. Conversion of Phenylalanine to Tyrosine |
| R. Homocystinuria | iii. Tyrosine degradation |
| S. Argininemia | iv. Methionine metabolism |
| v. Urea Synthesis |
A woman heterozygous for colour blindness marries a colour-blind man. What would be the ratios of carrier daughters, colour-blind daughters, normal sons, and colour-blind sons in the F1 generation?
