Stereoisomerism

IMPORTANT

Stereoisomerism: Overview

This Topic covers sub-topics such as Optical Isomerism, Geometrical Isomerism, Stereoisomerism, Conformational Isomerism, Types of Stereoisomerism and, Syn-Anti Geometrical Isomerism

Important Questions on Stereoisomerism

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IMPORTANT

Define syn form of a compound.

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IMPORTANT

Taxotere (docetaxel) is an anticancer drug that can be synthesised using chiral auxiliaries. A fragment of its structure is shown in figure, deduce the number of possible stereoisomers of this structural fragment.

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Chirality plays an important role in the action of drugs. Using an asterisks (*) ,identify the chiral carbon atom in a copy of the structure of thalidomide.

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Would cis-2,3-dichloro-2-butene have a larger or smaller dipole moment than cis-1,2-dichloroethene?